The first-trimester combined screening test is performed between weeks 12 and 14 of pregnancy and includes a blood test and a fetal ultrasound examination. It is the most accurate early screening method for detecting fetal chromosomal disorders, including Down syndrome.

In addition, the screening helps identify more than one hundred possible severe fetal structural abnormalities and provides important information about the course of the pregnancy. The screening does not focus solely on assessing chromosomal disorders but also enables early evaluation of the mother’s risk of developing serious pregnancy-related complications.

The test provides valuable information about both fetal and maternal health risks and is recommended for all pregnant women, regardless of age or previous risk factors.